BORING!
(Did you know April is national sheet setup month?)
I've modified the drawing area object. Whee! It is simpler, clearer, and just a bit more spacious. It also allows you to disregard the grid in PlotMaker, which allowed me to cut the layout book templates from 5 to 2.
The rectangle is the available drawing area. The ticks on the corners line up with the title block, and set a 3/16" margin around the sheet. Alignment hotspots should be placed on these ticks. The ticks along the edges at each corner are for aligning plan dimensions.